1-dan master of the unyielding fist of Bayesian inference
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[N] Meta releases Llama 3

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[N] Meta releases Llama 3 submitted by /u/we_are_mammals to r/MachineLearning
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clumma
5 hours ago
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A new understanding of tinnitus and deafness could help reverse both

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https://www.newscientist.com/article/mg26234870-800-a-new-understanding-of-tinnitus-and-deafness-could-help-reverse-both/

ChatGPT summary: The article delves into the intricate relationship between tinnitus and hearing loss, shedding light on recent breakthroughs and potential treatments. It begins by recounting the experience of James Rand, a former DJ who developed tinnitus from prolonged exposure to loud music. Despite traditional treatments offering little relief, recent research has led to the development of neurostimulation devices that can reduce tinnitus volume, with some treatments showing promise for complete silence.

Moreover, investigations into the connection between tinnitus and hearing loss have unveiled a hidden form of deafness. This hidden hearing loss, which affects individuals with normal hearing test results but experience difficulty understanding speech in noisy environments, has challenged previous theories linking tinnitus solely to hair cell damage.

Studies in mice have revealed that cochlear nerve fibers, rather than hair cells, may be vulnerable to damage from noise exposure, leading to hidden hearing loss. This discovery has prompted research into regrowing damaged nerve fibers using natural signaling molecules like neurotrophins. Additionally, strategies aimed at reducing tinnitus symptoms through electrical stimulation have shown efficacy in clinical trials.

However, while these advancements offer hope for new treatments, current options mainly focus on helping individuals manage tinnitus symptoms rather than curing the condition. The article stresses the importance of preventive measures to avoid hearing damage, such as limiting exposure to loud noise and using protective gear like earplugs.

Overall, the article provides a comprehensive overview of recent developments in understanding and treating tinnitus, highlighting the complexity of the condition and the potential for future breakthroughs.

Twitter-Account from NewScientist: https://twitter.com/newscientist/status/1780964106154938650?t=4xtAvADdCan89IG8MQnQ9w&s=19

submitted by /u/ShoddyPerformance558 to r/tinnitusresearch
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clumma
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Rodent Aging Interventions Database (RAID) — LEV Foundation

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Rodent Aging Interventions Database (RAID) — LEV Foundation submitted by /u/lleonard188 to r/longevity
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Small extracellular vesicles from young plasma reverse age-related functional declines by improving mitochondrial energy metabolism

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Small extracellular vesicles from young plasma reverse age-related functional declines by improving mitochondrial energy metabolism submitted by /u/Long_on_AMD to r/longevity
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clumma
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Young Plasma Rejuvenates Blood DNA Methylation Profile, Extends Mean Lifespan, and Improves Physical Appearance in Old Rats

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submitted by /u/chromosomalcrossover to r/longevity
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clumma
1 day ago
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That IACR preprint

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For those who don’t yet know from their other social media: a week ago the cryptographer Yilei Chen posted a preprint, eprint.iacr.org/2024/555, claiming to give a polynomial-time quantum algorithm to solve lattice problems. For example, it claims to solve the GapSVP problem, which asks to approximate the length of the shortest nonzero vector in a given n-dimensional lattice, to within an approximation ratio of ~n4.5. The best approximation ratio previously known to be achievable in classical or quantum polynomial time was exponential in n.

If it’s correct, this is an extremely big deal. It doesn’t quite break the main lattice-based cryptosystems, but it would put those cryptosystems into a precarious position, vulnerable to a mere further polynomial improvement in the approximation factor. And, as we learned from the recent NIST competition, if the lattice-based and LWE-based systems were to fall, then we really don’t have many great candidates left for post-quantum public-key cryptography! On top of that, a full quantum break of LWE (which, again, Chen is not claiming) would lay waste (in a world with scalable QCs, of course) to a large fraction of the beautiful sandcastles that classical and quantum cryptographers have built up over the last couple decades—everything from Fully Homomorphic Encryption schemes, to Mahadev’s protocol for proving the output of any quantum computation to a classical skeptic.

So on the one hand, this would substantially enlarge the scope of exponential quantum speedups beyond what we knew a week ago: yet more reason to try to build scalable QCs! But on the other hand, it could also fuel an argument for coordinating to slow down the race to scalable fault-tolerant QCs, until the world can get its cryptographic house into better order. (Of course, as we’ve seen with the many proposals to slow down AI scaling, this might or might not be possible.)

So then, is the paper correct? I don’t know. It’s very obviously a serious effort by a serious researcher, a world away from the P=NP proofs that fill my inbox every day. But it might fail anyway. I’ve asked the world experts in quantum algorithms for lattice problems, and they’ve been looking at it, and none of them is ready yet to render a verdict. The central difficulty is that the algorithm is convoluted, and involves new tools that seem to come from left field, including complex Gaussian functions, the windowed quantum Fourier transform, and Karst waves (whatever those are). The algorithm has 9 phases by the author’s count. In my own perusal, I haven’t yet extracted even a high-level intuition—I can’t tell any little story like for Shor’s algorithm, e.g. “first you reduce factoring to period-finding, then you solve period-finding by applying a Fourier transform to a vector of amplitudes.”

So, the main purpose of this post is simply to throw things open to commenters! I’m happy to provide a public clearinghouse for questions and comments about the preprint, if those studying it would like that. You can even embed LaTeX in your comments, as will probably be needed to get anywhere.


Unrelated Update: Connor Tabarrok and his friends just put a podcast with me up on YouTube, in which they interview me in my office at UT Austin about watermarking of large language models and other AI safety measures.

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clumma
2 days ago
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